Abstract

The Integrated Zero-Heat Neural Interface (IZHNI) is a conceptual TRL-4 engineering architecture defining a coupled thermal–fluidic–mechanical system designed to manage localized electronic heat loads (~250 mW) in extreme spatial constraint environments relevant to neural interface technologies.

This disclosure does not describe a medical device or implantable system, but rather a simulation-ready and benchtop-testable thermal management framework intended for independent validation in non-biological environments.

The system integrates three coupled subsystems: (1) anisotropic thermal biasing layers that preferentially direct heat flow, (2) parallel microfluidic heat extraction channels operating in a low-Reynolds chaotic advection regime, and (3) a mechanically compliant substrate designed to reduce strain transfer in soft-tissue-mimicking environments.

The architecture is defined entirely through bounded physical parameters, including thermal resistance constraints, fluidic pressure limits, mechanical strain thresholds, and explicit multiphysics coupling conditions. A complete CFD-ready parameter set, failure mode analysis, and benchtop validation protocol are included.

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.

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