Abstract
The Lazarus-Train is a complete, open-source research platform combining three proven technologies—helical vortex preconditioning, 33 MHz traveling surface acoustic wave (TSAW) pathogen disruption, and magnetic nanoparticle trapping—into a modular skid-mounted system for biofluid conditioning studies. Unlike conventional size-based filtration (ECMO, dialysis), this physics-based approach achieves >90% particle separation with < 2% hemolysis through density-selective acoustic lysis and continuous-flow magnetic cleanup.
Key Innovation: First integration of J-Groove vortex de-agglomeration (GCI #18), TSAW additive-free lysis on LiNbO3 substrate, and Permalloy antidot arrays for viral debris capture—all controlled by Arduino with hard safety interlocks. Total build cost: $2,475 using commercial off-the-shelf components. Complete assembly: 3.5 hours. TRL 5 (lab-validated integration ready).
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Recommended Citation
Caldwell, Michael Victor Mr., "GCI #281 — LAZARUS-TRAIN v2.0", Technical Disclosure Commons, ()
https://www.tdcommons.org/dpubs_series/9729