Abstract
This document, produced with the assistance of ChatGPT o3 and ChatGPT 5 Thinking, is released under the Apache 2.0 licence. It is a voluntary defensive publication (prior art) and therefore enters the prior art upon release under the applicable patent statutes EPC Art. 54(2) (European Patent Convention), French IPC Art. L 611-11 (French Intellectual Property Code), 35 U.S.C. §102(a) (United States Patent Act), Chinese Patent Law Art. 22(5) (中华人民共和国专利法), and Japanese Patent Act Art. 29(1) (特許法). We disclose 77 enabling embodiments spanning assays/kits (telomeres, DNAm clocks, glycan-age, proteome, microbiome, metabolome, cfDNA-CHIP, mtDNA, 8-oxo-Gsn, NAD⁺), devices/sensors (AGE autofluorescence, VOP/PPG, continuous/interstitial NAD), AI/analytics (composite age, brain-age MRI, multimodal transformer, federated/DP, MLOps/QC), closed-loop protocols (senolytics, NAD scheduling, mTOR pre-vaccination, TRIIM-like, hormesis), delivery (microneedles, exosomes), imaging (MRI/MRS), and compliance/operations (FHIR consent, ATEX enclosures, logistics, calibration-as-a-service). Each proposal includes SOP-level parameters, IPC/CPC classifications, and timestamp proof (RFC 3161 / FreeTSA). Original publication on Zenodo : https://zenodo.org/records/16782696.
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Recommended Citation
Pillet, Xavier, "Longevity OS: Open Compendium of Aging Biomarkers and Open-Source Intervention Protocols", Technical Disclosure Commons, (August 11, 2025)
https://www.tdcommons.org/dpubs_series/8451