Abstract
CVTCC-1.0 is a research system designed to investigate a previously under-integrated physiological question:
Does an abnormal cranial thermal response occur together with measurable changes in internal-jugular venous transport, and can the coupled response be detected earlier or more reliably than either measurement alone?
The system does not assume that such coupling exists.
Instead, CVTCC-1.0 deliberately creates a small, controlled thermal perturbation at the body surface and measures the resulting time-dependent thermal response at multiple locations while simultaneously recording:
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left and right neck thermal response,
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local heat flux,
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skin temperature,
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environmental temperature and humidity,
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respiration,
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cardiac timing,
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body position,
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motion,
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and venous-flow reference measurements during validation.
The system then calculates a deterministic Cranio-Venous Thermal Coupling Response (CVTCR) from the measured transfer functions.
The purpose is not to diagnose thrombosis.
The purpose is to determine experimentally whether changes in jugular venous transport and cranial thermoregulation become measurably coupled during simulated microgravity, exercise, rest, thermal stress, or other spaceflight analog conditions.
Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 License.
Recommended Citation
Caldwell, Michael Victor Mr., "CVTCC-1.0 Caldwell Cranio-Venous Thermal Coupling Challenge System A Non-Invasive Research Architecture for Simultaneous Detection of Jugular Flow-State Changes and Cranial Thermoregulatory Response During Simulated Microgravity", Technical Disclosure Commons, (October 01, 2026)
https://www.tdcommons.org/dpubs_series/11942