Abstract

A system and method for inducing controlled mechanical destabilization in heterogeneous biological tissue through a conditionally assembling, multi-component material matrix that encodes mechanical failure pathways and is subsequently actuated via staged, multi-frequency external field interaction. The system operates without cytotoxic agents, instead leveraging spatially selective coupling between the assembled matrix and externally applied acoustic fields to induce progressive structural failure and self-limiting resolution.

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Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.

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