Abstract
The carbobenzyloxy (Cbz) group is widely used for protecting amines in synthetic chemistry due to its stability and ease of removal. Traditionally, Cbz deprotection relies on palladium-catalyzed hydrogenolysis under hydrogen gas, which, while effective, presents several drawbacks—particularly in commercial-scale applications
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Recommended Citation
Anonymous, "Acid-Mediated Deprotection of Cbz Groups: A Convenient and Scalable Alternative to Pd-Catalyzed Hydrogenolysis", Technical Disclosure Commons, (August 12, 2025)
https://www.tdcommons.org/dpubs_series/8457
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