Abstract

The present disclosure relates to a process for the preparation of (S)-5-amino-3-(4-((5-fluoro-2-methoxybenzamido)methyl)phenyl)-1-(1,1,1-trifluoro propan-2-yl)-1H-pyrazole-4-carboxylic acid of formula-3 which is useful in the preparation of Pirtobrutinib of formula-1. Structures of compound of formula-3 and Pirtobrutinib of formula-1 are shown below:

Formula-1 Formula-3.

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