Abstract
Ponatinib hydrochloride, has a chemical name 3-(imidazo [1,2-b]pyridazin-3ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl} benzamide hydrochloride. Ponatinib hydrochloride is a kinase inhibitor which is indicated for the treatment of chronic myeloid leukaemia (CML) that is resistant or intolerant to prior tyrosine kinase inhibitor therapy or Philadelphia chromosome positive acute lymphoblastic leukaemia (Ph+ALL) that is resistant or intolerant to prior tyrosine kinase inhibitor therapy.
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Recommended Citation
Anonymous, "IMPROVED PROCESS FOR PREPARATION OF PONATINIB HYDROCHLORIDE", Technical Disclosure Commons, (January 10, 2025)
https://www.tdcommons.org/dpubs_series/7718