Improved process for the preparation of 4-((6,7-dimethoxyquinolin-4-yl)oxy)aniline

Inventor(s)

MSN Laboratories Private Limited, R&D Center; Srinivasan Thirumalai Rajan; M. Ramakrishna; Chandrakanth Rao SirigiriFollow

Abstract

Abstract:

Improved process for the preparation of 4-((6,7-dimethoxyquinolin-4-yl)oxy)aniline of formula-1, which is represented by the following structural formula:

which is key intermediate for the preparation of Cabozantinib, which is chemically known as N-(4-(6,7-dimethoxyquinolin-4-yloxy)phenyl)-N’-(4­fluorophenyl)cyclopropane-1,1-dicarboxamide or its salts such as malate, fumarate or etc.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 License.

Recommended Citation

MSN Laboratories Private Limited, R&D Center; Srinivasan Thirumalai Rajan; M. Ramakrishna; Chandrakanth Rao Sirigiri, "Improved process for the preparation of 4-((6,7-dimethoxyquinolin-4-yl)oxy)aniline", Technical Disclosure Commons, (October 15, 2024)
https://www.tdcommons.org/dpubs_series/7428