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Patterned microwell structures are ubiquitous in many applications such as biochips, microfluidics, single-cell analysis, and patterning of various functional materials including optical and magnetic nanoparticles. Conventional microwell fabrication methods are based on laser etching and lithography, which provide high resolution at micro and nanometric scales. However, these methods are expensive, multistep, patterning rigidity and limited to small area fabrication. This disclosure describes a method to fabricate microwell structures using an inkjet printer and a light responsive material (photopolymer), wherein it is simple, inexpensive, prompt and requires no further cleaning prior use. In addition, the patterning of the microwells is no longer rigid and can be print-on-demand using the inkjet printer.

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Creative Commons License
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