Abstract

IMPROVED PROCESS FOR THE PREPARATION OF 4-((4-METHYLPIPERAZIN-1-YL)METHYL)-3-(TRIFLUOROMETHYL)ANILINE

The present invention relates to an improved process for the preparation of 4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline formula (1).

Formula (1)

4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline is used in the preparation of Ponatinib hydrochloride.

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