Title
Improved process for the preparation of 1-((4-fluorophenyl)carbamoyl) cyclopropanecarboxylic acid
Abstract
Abstract:
Improved process for the preparation of 1-((4-fluorophenyl)carbamoyl) cyclopropanecarboxylic acid of formula-1, which is represented by the following structural formula:
which is key intermediate for the preparation of Cabozantinib (S)-malate, which is chemically known as N-(4-(6,7-dimethoxyquinolin-4-yloxy)phenyl)-N’-(4fluorophenyl) cyclopropane-1,1-dicarboxamide, (2S)-hydroxybutanedioate.
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Recommended Citation
MSN Laboratories Private Limited, R&D Center; Srinivasan Thirumalai Rajan; M. Kishore kumar; M. Ramakrishna; Mukunda Reddy Panduga, Chandrakanth Rao Sirigiri, "Improved process for the preparation of 1-((4-fluorophenyl)carbamoyl) cyclopropanecarboxylic acid", Technical Disclosure Commons, (November 21, 2022)
https://www.tdcommons.org/dpubs_series/5508