Process for the preparation of 3-(aminomethyl)-4,6-dimethylpyridin-2(1H)-one hydrochloride

Inventor(s)

MSN Laboratories Private Limited, R&D Center, Srinivasan Thirumalai Rajan, Sajja Eswaraiah, Vijayavitthal T. Mathad, Gandham Shyam Kiran babu, Lunavath KumaraswamyFollow

Abstract

Abstract:

Process for the preparation of 3-(aminomethyl)-4,6-dimethylpyridin-2(1H)-one hydrochloride of formula-1, which is represented by the following structural formula:

which is key intermediate for the preparation of Tazemetostat hydrobromide, which is chemically known as [1,1’-Biphenyl]-3-carboxamide, N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-5[ethyl(tetrahydro-2H-pyran-4-yl)amino]-4-methyl-4’-(4-morpholinyl methyl)-, hydrobromide (1:1).

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 License.

Recommended Citation

MSN Laboratories Private Limited, R&D Center, Srinivasan Thirumalai Rajan, Sajja Eswaraiah, Vijayavitthal T. Mathad, Gandham Shyam Kiran babu, Lunavath Kumaraswamy, "Process for the preparation of 3-(aminomethyl)-4,6-dimethylpyridin-2(1H)-one hydrochloride", Technical Disclosure Commons, (September 28, 2022)
https://www.tdcommons.org/dpubs_series/5410