Systems and methods for defense against biometric reproduction attack are disclosed. The system includes one or more mobile devices installed with a security feature integrated to the operating system or installed to the device as an app. The security feature is in communication with a server installed with a mobile device management solution. The device includes a multi-factor authentication system including at least one biometric authenticator and at least one non-biometric authenticator. The method includes prompting for biometric authentication, if the network is reachable. In the absence of an active network, the server may instruct the device to stop using a biometric authentication and request the user for a multifactor authentication. The systems and methods provide for full enterprise connectivity on devices with a biometric authentication system. The present disclosure allows the network administrators to address biometric reproduction attacks with variable levels of risk tolerance.

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