IMPROVED PROCESS FOR THE PREPARATION OF UPADACITINIB AND ITS INTERMEDIATES

Inventor(s)

MSN Laboratories Private Limited, R & D Center; Srinivasan Thirumalai Rajan; Sajja Eswaraiah; Sagyam Rajeshwar Reddy; Ramachandra Puranik; Keshavareddy Navin Kumar Reddy; Parigi Raghavendar Reddy.Follow

Abstract

The present invention relates to an improved process for the preparation of (3S,4R)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide.

The present invention also relates to an improved process for the preparation of formula (6), which is used as an intermediate in the preparation of (3S,4R)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide of formula (1).

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Recommended Citation

MSN Laboratories Private Limited, R & D Center; Srinivasan Thirumalai Rajan; Sajja Eswaraiah; Sagyam Rajeshwar Reddy; Ramachandra Puranik; Keshavareddy Navin Kumar Reddy; Parigi Raghavendar Reddy., "IMPROVED PROCESS FOR THE PREPARATION OF UPADACITINIB AND ITS INTERMEDIATES", Technical Disclosure Commons, (July 19, 2022)
https://www.tdcommons.org/dpubs_series/5269