Abstract
Abstract:
The present invention relates to a novel process for the preparation of methyl N-{(2S)-1-[(4-{3-[5-chloro-2-fluoro-3(methanesulfonamido)phenyl]-1-(propan-2-yl)-1H-pyrazol-4-yl}pyrimidin-2-yl)amino]propan-2yl}carbamate represented by the following structural formula.
Formula-1
The present invention also relates to amorphous Encorafenib and amorphous solid dispersions of Encorafenib.
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Recommended Citation
MSN Laboratories Private Limited, R&D Center; Srinivasan Thirumalai Rajan, Sajja Eswaraiah, Vijayavitthal T. Mathad, Saladi Venkata Narasayya, Kammari Bal Raju, Laxman Gande, Nagunuri Ganapathi Chary, "Novel process for the preparation of methyl N-{(2S)-1-[(4-{3-[5-chloro-2-fluoro-3 (methanesulfonamido)phenyl]-1-(propan-2-yl)-1H-pyrazol-4-yl}pyrimidin-2-yl)amino] propan-2yl}carbamate", Technical Disclosure Commons, (July 18, 2022)
https://www.tdcommons.org/dpubs_series/5265