Improved process for the preparation of 1-(4-bromo-5-[1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl]-2-fluorophenyl)-3-phenylurea

Inventor(s)

MSN Laboratories Private Limited, R&D Center; Srinivasan Thirumalai Rajan; Sajja Eswaraiah; Vijayavitthal T. Mathad; Jakku Malleswara ReddyFollow

Abstract

The present invention relates to an improved process for the preparation of Ripretinib, crystalline forms of Form-M, Form-S and Form-N of Ripretinib, process for the preparation of crystalline forms and novel intermediate compound which is useful for the preparation of Ripretinib.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 License.

Recommended Citation

MSN Laboratories Private Limited, R&D Center; Srinivasan Thirumalai Rajan; Sajja Eswaraiah; Vijayavitthal T. Mathad; Jakku Malleswara Reddy, "Improved process for the preparation of 1-(4-bromo-5-[1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl]-2-fluorophenyl)-3-phenylurea", Technical Disclosure Commons, (July 13, 2022)
https://www.tdcommons.org/dpubs_series/5258